·From: Interstate 26. Exit 221A will merge onto US Highway 17 South. Travel approximately one mile, the Best Western Charleston Downtown Hotel is located on the right, after Arby?s fast food restaurant. ·From: Highway 17 South. Follow US Highway 17 South into Charleston. US 17 South will cross over a large bridge (Arthur Ravenel Jr. Bridge). At the foot of the bridge, continue traveling on US 17 South for about one mile. The Best Western Charleston Downtown Hotel will be on the right, after Arby?s fast food restaurant. ·From: Highway 17 North. Follow US Highway 17 North into Charleston. Cross over the Ashley River Bridge. While on the bridge, travel in the second from the right lane and exit onto Lockwood. At the stoplight, turn left onto Lockwood Boulevard going North. Follow Lockwood Boulevard under the bridge, the Best Western Charleston Downtown Hotel entrance is on the right.